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DescriptionCozaar (Losartan) is indicated for the treatment of hypertension
Drug UsesLosartan is indicated for the treatment of hypertension. It may be used alone or in combination with other agents. It has less of an effect in black patients, similar to ACE inhibitors, such as captopril (Capoten), enalapril (Vasotec), and lisinopril (Zestril).
How TakenLosartan may be given with or without food. Losartan is metabolized in the liver by cytochrome P450 enzymes to an active metabolite that is responsible for most of the drug activity. Reduction in dose by 50% is suggested in patients with impaired liver function.
